HMGB2 and stroke disorder: Western blots of the lysates from microglia showed that the levels of Hmgb2 in stroke mice were elevated by more than 6-fold of sham controls (0.17 ± 0.024 in sham versus 1.02 ± 0.13 in stroke group, mean ± SEM, n = 5 mice/per group, p = 0.0021, t-tests, Fig. 2B, C).