We found that the occurrence rate of sleep apneas of 2-month-old Cdkl5 -/Y and Cdkl5 +/Y mice did not differ, while middle-aged Cdkl5 -/Y mice had more frequent apneas during non-rapid eye movement (NREM) sleep compared to Cdkl5 +/Y mice (Fig. 2A). Here, CDKL5 is linked to Sleep apnea.