TNF and hydrops fetalis: Serum levels of AST, ALT, TC, TG, FFA, LDL, glucose, insulin, and TNF-α were significantly higher in the HF group than those of the control, the Berberine, and Sitagliptin alone groups (*P<0.05) whereas the serum levels of HDL and adiponectin were lower in the HF group than those of other groups at 6 weeks post-treatment (Figures 2A-F, Figures 3A-E).