The result from the IB analysis (Figure 2A) indicated that p53 is more significantly induced in HCT116 +/+ colon cancer and H460 (p53 wt) lung cancer cells by n-INZ-C than that by INZ-C only, following 18 h treatment with DMSO (control), CD, and nanoparticle control (NPC), INZ-C or n-INZ-C. The gene discussed is TP53; the disease is malignant colon neoplasm.