All three components are expressed in the two pairs of PCa cells, with the levels of EZH2 slightly higher in ARCaPE-shEPLIN and unchanged in C4-2B-TaxR, EED unchanged in ARCaPE-shEPLIN and higher in C4-2B-TaxR, SUZ12 higher in ARCaPE-shEPLIN and unchanged in C4-2B-TaxR. The gene discussed is EZH2; the disease is posterior cortical atrophy.