For this purpose, we conducted bioinformatics analysis and a review of the literature to identify miRNAs targeting the 3'-untranslated regions (3'-UTR) of KDM6B. We identified miR-138-5p, miR-146a, and miR-20a-3p as candidate miRNAs mediating the inhibition by cancer cells of the expression of KDM6B in macrophages (Figure 1A). Here, KDM6B is linked to cancer.