First, coculture with tumor cells inhibited the expression of M1-related genes encoding IL-6, TNF-α, and IL-1β and increased the expression of M2-related genes encoding CD163, Arg1, IL-10, TGF-β, and VEGFA, as well as expression of TNF-α and CD163 at protein level. Here, TGFB1 is linked to neoplasm.