PGC and gastric cancer: Considering a previous report describing that a low PGC expression level was correlated with shorter OS of GC patients 46, we believed that the low expression of hsa_circ_0001483 and hsa_circ_0001324 attenuated their capacity to absorb hsa-let-7c, thus down-regulating PGC expression, which may affect the prognosis of GC patients.