Using TCGA data, we performed survival curve analysis of the differentially expressed Rho family GTPases genes such as Rac3, RhoBTB1, RhoBTB3, RhoC, RhoV, RhoB, RhoBTB2, RhoF, RhoQ, and RhoU in non-M3 AML patients. The gene discussed is RHOF; the disease is acute myeloid leukemia.