Using TCGA data, we performed survival curve analysis of the differentially expressed Rho family GTPases genes such as Rac3, RhoBTB1, RhoBTB3, RhoC, RhoV, RhoB, RhoBTB2, RhoF, RhoQ, and RhoU in non-M3 AML patients. Here, RHOBTB1 is linked to acute myeloid leukemia.