Since these pRS-related hub genes (EGFR, INHBA, CFLAR, DAPK2, TSC2, CAPN10, MBTPS2, PEX14, FADD and ST13) show strong heterogeneity in different cells, we speculate that these genes alone can predict cellular composition to reflect the microenvironment of tumor tissues. The gene discussed is DAPK2; the disease is neoplasm.