In contrast, this phenomenon is relatively rare in follicular carcinoma and anaplastic (undifferentiated) carcinoma, suggesting that the expression of FUT8 may be a key factor in the progression of papillary thyroid carcinoma (rather than follicular carcinoma), and a decrease in FUT8 expression may be related to anaplastic transformation 64. This evidence concerns the gene FUT8 and thyroid gland follicular carcinoma.