The results indicated that the module nodes were mainly enriched in cell cycle, microRNAs in cancer, pathways in cancer, apoptosis, central carbon metabolism in cancer, pancreatic cancer, proteoglycans in cancer, focal adhesion, PI3K-Akt, FoxO, p53, Sphingolipid, AMPK and mTOR signaling pathway. Here, AKT1 is linked to familial pancreatic carcinoma.