The results showed that these five genes, especially ADORA1, could activate EMT, Hormone ER, PI3K/AKT, RAS/MAPK, TSC/mTOR pathways, and inhibit RTK, Hormone AR, DNA Damage Response, Cell Cycle, Apoptosis pathways to exert regulatory effects in cancer process (Figure 10B). The gene discussed is ADORA1; the disease is cancer.