In summary, we are delighted that our present study provides strong and consistent two-fold evidence for the first timeꓽfirstly that VES-induced anti-tumour activity on human cervical cancer cells is mediated, at least in part, by the CD47-SIRPα pathway in vivo and in vitro, and secondly that the phagocytosis of tumour cells by macrophages is implicated in this process. This evidence concerns the gene SIRPA and cervical cancer.