Moreover, detection of GATA6 in exhaled breath condensate seem to be an efficient diagnosis for non-invasive LC 61, and GATA6 can induce terminal differentiation and growth arrest in Tyrosine Kinase Inhibitors (TKI) resistant NSCLC cells by inhibiting EGFR and Wnt signaling activation 62. This evidence concerns the gene EGFR and non-small cell lung carcinoma.