Moreover, detection of GATA6 in exhaled breath condensate seem to be an efficient diagnosis for non-invasive LC 61, and GATA6 can induce terminal differentiation and growth arrest in Tyrosine Kinase Inhibitors (TKI) resistant NSCLC cells by inhibiting EGFR and Wnt signaling activation 62. The gene discussed is EGFR; the disease is laryngotracheoesophageal cleft.