Naoki et al. reported that only 47 of 348 cases of lung adenocarcinoma had positive GATA6 expression (13.5%) and GATA6 has no significant influence on OS or DFS using multivariate analysis 17, while GATA6 was remarkably reduced in squamous cell lung carcinoma tissues and can inhibit the proliferation and migration of squamous cell lung carcinoma cells 11. The gene discussed is GATA6; the disease is squamous cell lung carcinoma.