We found that 100 μM of APY29 significantly upregulated XBP1 expression in both ABC-DLCBL and GCB-DLBCL cells, which in turn promoted CXCR4 and CD44 expression, while the inhibition by the same concentration of STF-083010 was not obvious (Figure 4D). The gene discussed is CD44; the disease is aneurysmal bone cyst.