The high expression of GTPBP2 was positively correlated with the late stage of TNM stage (P = 0.005 <0.05), and was also positively correlated with lymph node metastasis (P = 0.014 <0.05), not related to age, gender, histological type and degree of differentiation. The gene discussed is GTPBP2; the disease is metastatic malignant neoplasm in the lymph nodes.