CD53 and obesity due to melanocortin 4 receptor deficiency: For example, many chemicals have been identified that affect the expression of CD53 and lead to obesity, including bisphenol A, cadmium chloride, carbon tetrachloride, choline, cisplatin, dexamethasone, dietary fats, diethylstilbestrol, ethinyl estradiol, lipopolysaccharides, methionine, parathion, phenobarbital, resveratrol, sodium selenite, streptozocin, tamoxifen, testosterone enanthate, tetrabromobisphenol A, tetrachlorodibenzodioxin, and tretinoin.