pCons Treatment Increased CD4+FoxP3+ Regulatory T Cells and Significantly Reduced Percent Expression and Median Fluorescence Intensity of CTLA-4 (Cytotoxic T-Lymphocyte-Associated Proten-4) in CD8+ T Cells of BWF1 Lupus Mice. The gene discussed is CD8A; the disease is systemic lupus erythematosus.