Despite the positive correlation between DKK1 and CTNNB1 mRNA levels and protein levels, positive tissue microarray data of the two proteins did not match completely from hepatocellular carcinomas patients, suggesting that DKK1 expression could be mediated by other molecules, for instance, progesterone and transforming growth factor-β1 (TGFβ1) (45, 49, 50). This evidence concerns the gene DKK1 and hepatocellular carcinoma.