IL10 and infection: Our findings are inconsistent with those from previous reports showing that NLRP3 inflammasome assembly is suppressed in IL-10−/− DCs via inhibition of the P2X purinoceptor 7 receptor (P2X7R) and reduction in the levels of intracellular Ca2+, leading to inhibition of DCs apoptosis post infection with C. muridarum (32).