For the E187A mutant, viral infection was inhibited by 1.6-folds by MxB, increased by 86% in Tat-NLS-MxBΔ(1–25) expressing cells, inhibited by 5.2-folds in Rev-NLS-MxBΔ(1–25) expressing cells (Figure 6B). Here, MX2 is linked to viral infectious disease.