SREBF2 and hepatocellular carcinoma: An increasing number of studies have confirmed that SREBP2 indeed plays a cancer-promoting role by regulating cholesterol metabolism in HCC (Yang et al., 2019; Che et al., 2020; Liu et al., 2020), and SREBP2 has been proven to be the target of some anticancer drugs (Kim et al., 2018; Kim et al., 2019).