UGT1A1 and Gilbert syndrome: In the present research, we observe a frequency of 0.36 for UGT1A1*28, which is comparable to the 0.33 reported in a previous study on the prevalence of Gilbert's syndrome in the Chilean population, and where the presence of the UGT1A1*28 allele was determined indirectly by analyzing the rs6742078 (G > T) variant located in intron 1 of the UGT1A1 gene, which is also in strong linkage disequilibrium with UGT1A1*28 (Méndez et al., 2013).