KCNA3 and neoplasm: Previously, it was discussed that Kv1.3 on a cell membrane is involved in cell proliferation, and the Kv1.3 channel on mitochondria is involved in the regulation of cell apoptosis, among which Kv1.3 on mitochondria is considered as a new tumor marker, and decreased Kv1.3 expression on mitochondria can induce the apoptosis of tumor cells (Checchetto et al., 2019).