This plant, also called ticktrefoils, is a medicinal plant from Asia, that is used for breast cancer (Yoo et al., 2005); Maackia amurensis-Rupr (Fabaceae), is a tree also known as Amur maackia (Yoo et al., 2005; Grishchenko et al., 2016); Humulus lupulus L. (Cannabaceae) Methanolic plant extracts bind to ERα and ERβ. The gene discussed is ESR2; the disease is breast carcinoma.