JAK1 and ulcerative colitis: The contents of cytokines IL-6, TNF-α, IFN-γ, IL-17 A, and IL-10 and the phosphorylation of STAT3, JAK1, JAK2 in the colon of the MC group were significantly higher than those of the NC group (P< 0.05) (Figure 3), which indicated that there was obvious inflammation in the colon of the ulcerative colitis model mice.