Some studies have demonstrated that the protein expression of SGLT2 could be detected in the immortalized human primary hepatocytes HuS-E/2 cells, human hepatocellular carcinoma HepG2 cells and mouse hepatic tissue (Hawley et al., 2016; Kaji et al., 2018; Chiang et al., 2020). Here, SLC5A2 is linked to hepatocellular carcinoma.