SLC17A6 and Parkinson disease: For example, wildtype VGluT2 expression appears to be neuroprotective to DA neurons in PD mouse models (Dal Bo et al., 2008; Bérubé-Carrière et al., 2009; Shen et al., 2018; Steinkellner et al., 2018; Kouwenhoven et al., 2020), though VGluT2 overexpression appears to be neurotoxic to DA neurons (Steinkellner et al., 2018).