NLRP3 and myocardial infarction: Among them, MCC950 has been reported to be effective in a variety of preclinical immunopathological models, including cryopyrin-associated periodic syndrome, experimental autoimmune encephalomyelitis, Alzheimer disease, traumatic brain injury, atherosclerosis, cardiac arrhythmias, myocardial infarction, diabetes, steatohepatitis, and colitis [22–29].