On the other hand, the experiment in anti-IL-1β and NLRP3−/− knockout sections fully confirmed that in Balb/c mice, the disruption or block of the NLRP3 pathway could significantly improve the prognosis of VMC caused by CVB3 and greatly alleviate the pathological process of VMC. The gene discussed is IL1B; the disease is liver mesenchymal hamartoma.