In this article, we would like to figure out whether the overactivated NLRP3 inflammasome is involved in the pathogenesis of CVB3-induced VMC or not, to disclose the correlation and interaction between NLRP3 inflammasome and Th17 cells in VMC process, and to explore the therapeutic value of NLRP3 inhibition in viral myocarditis by means of IL-1β antibody and NLRP3 knockout. The gene discussed is IL1B; the disease is liver mesenchymal hamartoma.