They vigorously contribute to the anti-tumor immune response in many cancers (colon, breast, lymphoma, myeloma, melanoma, lungs, ovary and prostate) [6].γδ T cells perform these activities through cytotoxicity against tumor/infected cells like CD8+ T cells/NK cells and by regulating other immune cells (antigen presentationfunction) such as dendritic cells, macrophages and B cells [7-9]. Here, CD8A is linked to neoplasm.