IGHE and allergic rhinitis: Allergic rhinitis (AR) is a form of immunoglobulin E (IgE) mediated inflammation of the nasal mucosa in response to specific allergens, resulting in symptoms including itching, nasal obstruction, watery rhinorrhea, and sneezing in the absence of infection.1, 2 AR patients may also suffer from ocular symptoms, chronic cough, and postnasal drip, significantly reducing the quality of life in a subset of affected individuals.1