These observations are in line with biochemical reports showing higher concentrations of HO-1 in the serum of PD patients [58] and in PD brain homogenates [59], as well as increased HO-1 histopathological localization in the LB inclusions [60] and in glial cells (astrocytes and microglia) within PD SN [59]. The gene discussed is HMOX1; the disease is Parkinson disease.