NFE2L2 and neuroblastoma: Our data show that transient overexpression of wild type or mutant human A53T aSyn in cultured neuroblastoma N2A cells did not alter cellular NRF2 expression (Additional file 1: Fig. S9A, B), and was associated with only slightly increased ROS accumulation (Additional file 1: Fig. S9C; compare with hydrogen peroxide-H2O2 treated groups).