Moreover, Zhou et al. confirmed that SNHG16 is up-regulated in the serum of ALI patients, and knocking down SNHG16 in the LPS-treated lung cell injury model inhibits the expression of CC motif chemokine ligand 5 (CCL5) by sponging miR-146a-5p, thereby reducing the inflammatory injury of lung cells [9]. This evidence concerns the gene CCL5 and acute respiratory distress syndrome.