It was found that miR‐494‐3‐enriched MI‐DC‐EXs could be directly taken up by the cardiac microvascular endothelial cells (CMECs), significantly up‐regulate the expression of the VEGF in CMECs, and thereby enhance angiogenesis in the infarcted myocardium after experimental MI.52 This evidence concerns the gene VEGFA and myocardial infarction.