DMD and Duchenne muscular dystrophy: In addition, establishment of chemical variants (cv, with different point mutations) of mdx mice such as mdx2Cv, mdx3Cv, mdx4Cv, mdx5Cv, and other dystrophin-deficient lines: Dup2, MD-null, Dp71-null, mdx52 and mdx βgeo, have provided more possibilities to model human DMD, with each strain having some unique features [99].