KMT5A and neoplasm: Similarly, some studies have found that KMT5A is abnormally overexpressed in many tumors and is positively correlated with the prognosis of patients, which may promote tumor cells proliferation by enhancing aerobic glycolysis49 or lipid metabolism50, activating androgen-induced cell proliferation51, or inhibiting Numb-p53-mediated cell apoptosis45.