CHEK1 and Miyoshi myopathy: Because RNA-seq analysis revealed that CHEK1 expression was correlated with osteoclast differentiation (Fig. 2A–B), we evaluated MRI data from MM patients of the TT2 cohort and found that CHEK1 expression was higher in MM patients with bone lesions than in MM patients without bone lesions, as detected by MRI (Fig. 5A).