EPHB4 and metastatic malignant neoplasm in the lymph nodes: For MDA-MB-231 secretion, no q-values were below the threshold 0.1 but Lysosome-associated membrane glycoprotein 3 (LAMP3, p = 0.021), Tumor necrosis factor ligand superfamily member 12 (TWEAK, p = 0.024), Fibroblast growth factor 2 (FGF2, p = 0.027) and C–C motif chemokine 17 (CCL17, p = 0.049) were significantly associated to low grade tumors whereas, Proprotein convertase subtilisin/kexin type 9 (PCSK9, p = 0.013), Ephrin type-B receptor 4 (EPHB4, p = 0.015), Osteoprotegerin (OPG, p = 0.048) and Tumor necrosis factor receptor 2 (TNFR2, p = 0.048) correlated to lymph node metastases.