There was also no significant difference in family history of allergic diseases between the asthma (65.4 %) and the non-asthma (35.3 %) groups (p > 0.05) The positive rates of inhaled-allergen-specific IgE and food allergen-specific IgE in asthma group were 69.6 and 65.2 %, respectively, while the positive rates in non-asthma group were 47.1 and 47.1 %, respectively. The gene discussed is IGHE; the disease is allergic disease.