In wheezing children diagnosed with asthma, the level of peripheral blood CD4+CCR6+CRTH2+ was 1.6 %±0.8 %, while the level in children without asthma was 0.8 %±0.6 %.There was a significant difference in the level of CD4+CCR6+CRTH2+ memory Th2 cells children with asthma compared with the non-asthma group (p < 0.01) (Table 2; Fig. 1). Here, CD4 is linked to asthma.