Logistic regression analysis indicated that circulating CD4+CCR6+CRTh2+ cells (EXP, 8.986; 95 % CI,1.886–42.816) and wheezing frequency(EXP, 0.127; 95 % CI, 0.023–0.703)were high risk factors for asthma. Here, PTGDR2 is linked to asthma.