For each chamber we defined a set of enriched genes involved in the progression of several cardiovascular diseases: GWAS signals for atrial fibrillation were associated with 41 RA-Enriched genes, whereas GWAS signals for dilated cardiomyopathy were associated with Ventricles-Enriched MYH7, FHL2, TNNC1 and TNNI3 genes. This evidence concerns the gene MYH7 and dilated cardiomyopathy.