KEGG pathway analysis exhibited that some related signaling pathways were affected by emodin in the treatment of COVID-19, including IL-17 signaling pathway, MAPK signaling pathway, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, and TNF signaling pathway, as presented by KEGG pathway analysis (Supplementary Figure 1–5). This evidence concerns the gene IL17A and COVID-19.