CD4 and Hemophagocytosis: A prior study of 39 older adults with EBV+ nodal cytotoxic TCL showed intermittent bone marrow invasion in 11 patients (29%), thrombocytopenia in 21 (62%), and hemophagocytosis in 13 (38%), and lymphoma cells had CD4+ (15%), CD8+ (64%), and CD56+ (15%) T/NK-cell phenotypes [11].