Periventricular nodular heterotopia-7 (PVNH7, OMIM#617201) is an ultra-rare neurodevelopmental disease affecting proper neuronal migration during neurogenesis in cortex development caused by impaired E3-ubiquitin ligase NEDD4L (Neural Precursor Cell Expressed, Developmentally Downregulated 4; UniProtKB - Q96PU5). This evidence concerns the gene NEDD4L and periventricular nodular heterotopia 7.