To test this hypothesis we designed this study to analyze body composition, anthropometry, metabolic profiles and inflammatory cytokines, particularly IL- 6, IL-8, IL-10, IL-17, IL-18, IL-23, MIF, Hs CRP, TNF-α, PAI-1 leptin levels in children with and without OSA. The gene discussed is IL18; the disease is obstructive sleep apnea syndrome.