CFTR and cystic fibrosis: Mutations or polymorphisms in the cystic fibrosis transmembrane conductance regulator (CFTR) gene were detected in another study of 4 hypersecreting patients with asthma, with a neutrophilic inflammatory phenotype, bronchiectasis, pansinusitis and respiratory infections [2]; this would suggest that a possible explanation for airway mucus hypersecretion may be that having asthma results in a combination of asthma and an attenuated form of cystic fibrosis (CF) in patients with a genetic alteration in the CFTR gene.