KLK3 and prostate adenocarcinoma: LNCaP is an androgen-responsivehuman prostate adenocarcinoma cell line widely used to model key featuresof clinical disease, including secretion of KLK2 and KLK3 followingandrogen stimulation.8 LNCaP CM was treatedwith different concentrations of 3 for 1 h, and proteinswere separated by SDS–PAGE.