Conversely, treatment with 1 μM KLK2_bABP or KLK3_bABPhad no significant effect on the number of migrating LNCaP-K14 cells.Simultaneous treatment of LNCaP-K14 cells with 1 μM each KLK2_bABP,KLK3_bABP, and KLK14_bABP resulted in a significant decrease in cellmigration, suggesting that KLK14 activity is a key driver of PCa cellmigration, while KLK2 and KLK3 activities individually make minorcontributions. Here, KLK2 is linked to posterior cortical atrophy.