CD274 and neoplasm: Patients with PD-L1 1%-49% are less likely to experience tumor response with PD-1 blockade than chemotherapy (16.6% vs 29.0%), but any clinical benefit is more likely to be sustained, demonstrated by higher 1-year PFS (35.0% vs 21.8%) and 2-year PFS (16.6% vs 5.6%) rates.