METTL3 and type 2 diabetes mellitus: To investigate the correlation of m6A modifications with human transcripts expression in patients with T2DM, we collected methylated RNA immunoprecipitation (MeRIP)-seq and RNA-seq transcriptome samples from human islet β-cells, and found 15 differentially expressed m6A genes and used these for analysis, including METTL3, FTO, and YTHDF1, etc. We further identified the potential human transcripts associated with m6A genes based on the partial correlation coefficient.