PMF patients also showed many strong interactions (between IL-17a with IL-6Ra, CCL5, VEGF, GM-CSF, G-CSF and M-CSF; IL-10 with CXCL10 and GM-CSF; CCL5 with IFN-γ and VEGF; CXCL10 with GM-CSF; M-CSF with IFN-γ and VEGF-R2), while PV patients were highly different from the CTRL group and showed the lowest number of strong correlations (CXCL8 with IL-6, IL-12p70 and CCL2; IL-10 with GM-CSF and CXCL10; and M-CSF with IFN-γ). The gene discussed is KDR; the disease is acquired polycythemia vera.