JAK2V617F+ ET patients were high producers of CCL2, CXCL10, CXCL12, IL-1β, IL-6Ra, IL-18, and TNF-α; while CALR mutated were high producers of GM-CSF, G-CSF, HGF, IFN-γ, IL-12p70, and IL-17a. Here, CXCL12 is linked to essential thrombocythemia.