SAA1 and nonpapillary renal cell carcinoma: As shown in Figures 6A–D, high SAA1 levels could effectively distinguish advanced and metastatic ccRCC tissues from normal tissues (Normal/T4 (Figure 6A, AUC = 0.8157, p = 0.0008); Normal/N1 (Figure 6B, AUC = 0.8481, p < 0.0001); Normal/M1 (Figure 6B, AUC = 0.7917, p < 0.0001); Normal/G4 (Figure 6C, AUC = 0.8862, p < 0.0001); Normal/Stage IV (Figure 6D, AUC = 0.7737, p < 0.0001), but could not distinguish early ccRCC tissues from normal tissues.